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Over time, we transition from liking something to craving it—needing it. Addiction takes over the mind and harms the body and spirit. Today, we know much more about how do drugs affect the brain. We know addiction is actually a brain disease and how drugs and alcohol can hijack the brain. There is sound science explaining how and why addiction happens, and this information is powerful for helping people overcome the disease. First, let’s address the difference between addiction and abuse. Both impact the brain, but those who abuse substances are more likely to have success using willpower to kick a bad habit. Drug and alcohol abuse is when you use the substance in ways that are not healthy. That could mean reaching for that drink or six when you are stressed out and trying to wind down. It can mean taking too many prescription pills. Drug abuse is when you turn to substances to get a certain feeling: pleasure, escape, relaxation and so on. Drug abuse can be damaging to relationships and the body—but usually, a person can stop if he or she wants to. That is not the case with addiction. Addiction is when you can’t stop using drugs or alcohol, even if you want to stop. Addiction drives you to keep using even if a substance is ruining your health, relationships, and finances. You can’t stop thinking about using the substance you are addicted to no matter what. Why? Because addiction is a disease that changes the brain. Addiction Science: How Drugs Affect the Brain We used to think that willpower alone should be enough to stop an addiction. That just saying no was the answer, and people who are addicted could just choose to not use. But we know much more about addiction today and the effects of drugs and alcohol on the brain. People don’t choose to stay addicted to a substance—their brain demands the substance and more of it over time. Addiction is a brain disease, and here is how drugs and alcohol change the brain. The brain reacts to pleasure by releasing dopamine into the area of the brain known as the “pleasure center.” (This is technically called the nucleus accumbens .) Addictive substances give the pleasure center big-time rewards—lots of dopamine that immediately satisfy and create a surge of dopamine. Basically, addictive substances short-cut the brain’s pleasure system and make pleasure happen faster and more intensely. The brain gets strong signals and remembers those signals.

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